The Modular Optical Imaging System (OiS200) can perform Intrinsic Optical Imaging, Fluorescence Imaging, and Speckle Imaging. Intrinsic Optical Imaging and fluorescence are easy and minimally-invasive methods for observing brain activity in vivo over a large area of the cortex. Speckle Imaging quantifies cerebral blood flow on surface vessels. You will find a PDF document below with more information. Please click on the link.