DigiGait Imaging System
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DigiGait™ Imaging System uses patented technology to image the ventral (bottom) side of mice or rats as they walk on a motorized, transparent treadmill belt. One high-speed camera captures the dynamics of the paws and corresponding limbs as they approach the belt during the braking phase of stance, or move away from the belt during the propulsion phase of stance just before the swing phase.
The DigiGait™ Imaging System fully quantifies the stance and swing components of stride. Proprietary software automatically calculates stride length, stride duration, stride frequency, and numerous other spatial and temporal gait indices, for each limb. We have extended the application of this unique instrument to the study of a wide array of models, pathologies, and drug-induced ataxias.
DigiGait™ will become the assay of choice for phenotyping mouse models of neurodegenerative disease, arthritis, pain, and testing the efficacy of drugs to correct motor dysfunction.
The DigiGait™ Imaging system provides numerous spatial and temporal indices of posture and gait dynamics, including:
- Stride length
- Stance width
- Stance duration
- Swing duration
- Braking duration
- Propulsion duration
- Stride frequency
- Paw Angle
Applications include mouse models of:
- Amyotrophic Lateral Sclerosis
- Drug-induced ataxia
- Ethanol sensitivity
- Huntington’s Disease
- Parkinson’s Disease
- Spinal Muscular Atrophy